Objective: To determine the association between tuberculosis-related stigma and treatment adherence in adult patients treated at primary healthcare centers in Iquitos during 2025. Methods: Observational, analytical, cross sectional and prospective study. Adult patients diagnosed with tuberculosis and undergoing treatment were included, selected through stratified proportional random sampling. Two validated instruments were used: the Tuberculosis Stigma Scale (adapted to the Peruvian context) and the Morisky Green adherence questionnaire. Sociodemographic data were also collected. Statistical analysis was performed using SPSS, including frequencies, association tests (Chi-square or Fisher’s exact test), and prevalence ratios with 95% confidence intervals. A p-value < 0.05 was considered statistically significant. Results: Most participants were male, single or cohabiting, and had comple...