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artículo

Decreasing central line-associated bloodstream infections rates in intensive care units in 30 low- and middle-income countries: An INICC approach

Publicado por
Rosenthal, Victor D., Jin, Zhilin, Brown, Eric C., Dongol, Reshma, De Moros, Daisy A., Alarcon-Rua, Johana, Perez, Valentina, Stagnaro, Juan P., Alkhawaja, Safaa, Jimenez-Alvarez, Luisa F., Cano-Medina, Yuliana A., Valderrama-Beltran, Sandra L., Henao-Rodas, Claudia M., Zuniga-Chavarria, Maria A., El-Kholy, Amani, Agha, Hala, Sahu, Suneeta, Mishra, Shakti B., Bhattacharyya, Mahuya, Kharbanda, Mohit, Poojary, Aruna, Nair, Pravin K., Myatra, Sheila N., Chawla, Rajesh, Sandhu, Kavita, Mehta, Yatin, Rajhans, Prasad, Abdellatif-Daboor, Mohammad, Chian-Wern, Tai, Gan, Chin Seng, Mohd-Basri, Mat Nor, Aguirre-Avalos, Guadalupe, Hernandez-Chena, Blanca E., Sassoe-Gonzalez, Alejandro, Villegas-Mota, Isabel, Aleman- Bocanegra, Mary C., Bat-Erdene, Ider, Carreazo, Nilton Y., Castaneda-Sabogal, Alex, Janc, Jarosław, Hlinkova, Sona, Yildizdas, Dincer, Havan, Merve, Koker, Alper, Sungurtekin, Hulya, Dinleyici, Ener C., Guclu, Ertugrul, Tao, Lili, Memish, Ziad A., Yin, Ruijie

Publicado 2024

Enlace

Background: Central line (CL)-associated bloodstream infections (CLABSIs) occurring in the intensive care unit (ICU) are common and associated with a high burden. Methods: We implemented a multidimensional approach, incorporating an 11-element bundle, education, surveillance of CLABSI rates and clinical outcomes, monitoring compliance with bundle components, feedback of CLABSI rates and clinical outcomes, and performance feedback in 316 ICUs across 30 low- and middle-income countries. Our dependent variables were CLABSI per 1,000-CL-days and in-ICU all-cause mortality rates. These variables were measured at baseline and during the intervention, specifically during the second month, third month, 4 to 16 months, and 17 to 29 months. Comparisons were conducted using a two-sample t test. To explore the exposure-outcome relationship, we used a generalized linear mixed model with a Poisson dis...