In Peru, a surveillance system against Neisseria Gonorrhoeae is not implemented. We do not have information on the prevalence of resistance in patients with Neisseria gonorrhoeae infection in our Loreto region. The objective of this research was to determine antibiotic resistance against Neisseria gonorrhoeae in two periodic medical care centers in the city of Iquitos-Peru in the years 2017-2020. The observational research design, cross-sectional, retrospective descriptive design. A total of 51 samples were analyzed, finding a total of 22 positive cases for N. gonorrhoeae, of which 95.5% were isolated from male patients. The men had a mean age of 23 years, and the only female patient was 17 years old. The majority worked independently (36.4%), and 31.8% were students. 63.6% had basic school education studies and more than half (54.5%) belonged to the district of San Juan. The majority at...