Objective: To evaluate the relationship between caries experience and socioeconomic and clinical factors in children aged 5 to 12. Materials and methods: A cross-sectional study was conducted with a sample of 103 children aged 5 to 12 from Puerto Colombia (Colombia) between 2022 and 2023. Clinical, socioeconomic, and demographic data were obtained from medical records. Poisson generalized linear models with robust standard errors were fitted to evaluate the relationship between caries experience and both socioeconomic and clinical variables. Incidence rate ratios (IRR) and their 95% confidence intervals were presented for crude and adjusted models. Results: Caries experience was 94.85% (n = 98), with a median of 8 affected teeth (IQR = 5-11). Additionally, it was significantly higher in stratum 2 (IRR = 1.4; 95% CI: 1.042-1.956) in children without access to water and gas services (IRR =...