The frequent observation that certain pregnancies of patients with uterine anomalies make an evolution that is unrelated to the existing alteration, made us think that there should be seemingly imponderable factors that are responsible for this unequal development in them.

Advances in electron microscopy that allowed unravel the cellular ultrastructure, and biochemistry of hormone we clarified the molecular composition of hormones, are those that have allowed us to get to know the correlation between the cortico-hypothalamic-pituitary system and the female genital tract.