1
artículo
Publicado 2009
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Daniel Alcides Carrion’s experiment was a landmark in the history of Peruvian medicine, with much controversy, but perhaps the main topic of discussion is the cause of Carrion’s death. An objective fact has passed unnoticed in the last hours of the experiment: the administration of intravenous injections of phenic acid. In 1884, this was a therapy proposed for anthrax treatment in Peru. The doctors’ medical decision during Carrion’s agony probably did not consider giving blood transfusions to Carrion in order to experiment with this new treatment. They probably thought to repeat with bartonellosis the success described with phenic acid injections in a patient with anthrax, unaware of the now proven toxicity of phenic acid. The event precipitating Carrion’s death was probably phenic acid intoxication in a patient with bartonellosis in the anemic phase.
2
artículo
Publicado 2014
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Although most of the bacteria that cause disease in humans adapt to the Kochs postulates. Kochs postulates as the first model had to Bacillus anthracis, the bacterium that was first shown to be the cause of an infectious disease, whose life cycle was discovered by Koch. Oroya fever and Peruvian wart on one disease. Peruvian wart is an infection with a characteristic clinical pattern, caused by Bartonella bacilliformis. Recent published studies awarded as the cause of a new Peruvian wart bartonella, the Candidatus Bartonella ancashi. Analyzing research, the proposed causality of B. ancashi is based only on observational evidence: the association of the new bartonella in one patient with a clinical pattern similar to the wart Peruvian and the origin of the patient from an endemic area. With the new B. ancashi has not been investigated whether or not it meets all of Kochs postulates, ...
3
artículo
Publicado 2014
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Although most of the bacteria that cause disease in humans adapt to the Kochs postulates. Kochs postulates as the first model had to Bacillus anthracis, the bacterium that was first shown to be the cause of an infectious disease, whose life cycle was discovered by Koch. Oroya fever and Peruvian wart on one disease. Peruvian wart is an infection with a characteristic clinical pattern, caused by Bartonella bacilliformis. Recent published studies awarded as the cause of a new Peruvian wart bartonella, the Candidatus Bartonella ancashi. Analyzing research, the proposed causality of B. ancashi is based only on observational evidence: the association of the new bartonella in one patient with a clinical pattern similar to the wart Peruvian and the origin of the patient from an endemic area. With the new B. ancashi has not been investigated whether or not it meets all of Kochs postulates, ...
4
artículo
Publicado 2023
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Hermilio Valdizán is considered the father of peruvian medical historiography, he had the desire to write an “Encyclopedia” of the peruvian wart. Recent medical journals reproduce Valdizán's complaint of not receiving government support in the publication of a reference book on Carrión's disease that gathers all the research on the Carrión's disease however, the book dreamed by Hermilio Valdizán was published. The book entitled “Peruvian documents referring to Carrión's disease” was edited by Hermilio Valdizán himself and Celso Bambaren, it brings together the biographies of the main wart researchers and its research from Salazar to the mid-20th century. Valdizán's “Encyclopedia” of the peruvian wart is practically unknown to most researchers of Carrión's disease, it should be considered as a milestone in the investigation of Carrión's disease, since it brings toget...