La ocratoxina A (OTA) es una micotoxina altamente tóxica producida por algunas variedades de hongos, capaz de contaminar productos agroindustriales, lo que ha obligado a establecer normas de regulación en varios países. Por tal motivo, es necesario contar con métodos confiables y sensibles para su detección temprana, que puedan ser utilizados de manera rutinaria. Los nanosensores aptaméricos representan una alternativa que puede mejorar la detección de moléculas de interés, debido a la alta afinidad y selectividad de los biorreceptores aptaméricos por objetivos específicos. Además, el uso de nanomateriales de metales nobles permite desarrollar sensores a partir de sus propiedades ópticas, como la resonancia de plasmón superficial localizado (LSPR), al poder monitorear los cambios en la superficie y relacionarlo con la concentración de una sustancia de interés. En este tra...

Nanotechnology has provided endless tools to improve detection systems in the most diverse fields of science. One of those tools is the development of surface enhanced Raman spectroscopy (SERS) that promotes the amplification in 8-10 orders of magnitude of the Raman signals obtained by conventional methods. However, the success of this analytical technique depends on many factors such as the core material of the nanoparticles, their morphology and the adsorption pattern of the analytes on the metal surface, aspects that are not always considered when designing this type of sensors. This work has focus on the effect of these features using a reference molecule such as methylene blue (MB) and two coffee metabolites, trigonelline and chlorogenic acids (CGAs), known as potential quality markers of this agricultural product so important in Peru. Herein, we reported higher Raman signals when u...

Nanotechnology has provided endless tools to improve detection systems in the most diverse fields of science. One of those tools is the development of surface enhanced Raman spectroscopy (SERS) that promotes the amplification in 8-10 orders of magnitude of the Raman signals obtained by conventional methods. However, the success of this analytical technique depends on many factors such as the core material of the nanoparticles, their morphology and the adsorption pattern of the analytes on the metal surface, aspects that are not always considered when designing this type of sensors. This work has focus on the effect of these features using a reference molecule such as methylene blue (MB) and two coffee metabolites, trigonelline and chlorogenic acids (CGAs), known as potential quality markers of this agricultural product so important in Peru. Herein, we reported higher Raman signals when u...