The objective was to determine the relationship between sociodemographic factors and attitude towards vaccination against COVID-19, in inhabitants of the Iván Vásquez Valera Human Settlement, Iquitos. It is a quantitative, non experimental, descriptive, cross-sectional and correlational study; whose sample was 116 inhabitants. The survey and the home visit were used as techniques; a questionnaire on sociodemographic factors (Validity 88.75%) and an attitudinal scale of vaccination against COVID-19 (validity 87.50% and reliability 81.12%). The results were: 64.7% adults and 35.3% youth; 72.4% women and 27.6% men; 50.0% with secondary education, 36.2% primary and 13.8% technical/higher; 51.7% housewives; 28.4% are self-employed, 8.6% are students, 6.9% are public employees and 4.3% are construction workers; 56.9% Catholics and 43.1% Evangelicals/other religions; 44.0% came from peri-urba...