Eigteen patients with systemic rheumatoid arthritis have been studied from the c/inically, radiologically, pathologically and inmunologically. The characteristic of systemic rheumatoid arthritis and systemic lupus erithemathosis are similar in sorne patients, however those with the first disease do have much more severe and destructive articular changes as well as higher titers of rheumatoid factors, on the other hand those with systemic lupus have compromise of the kidneys with much more frequency and a/so higher antinuclear antibodies titer in serum. Systemic rheumatoid arthritis would be a bridge between the classical rheumatoid disease and systemic lupus. Positive antinuclear antibodies were found in the serum of sixteen patients and just in fourteen ones in synovial fluids. lt was frecuently found more than one antinuclear antibody pattern. The pheriferal and the specklel antinuclea...

Eigteen patients with systemic rheumatoid arthritis have been studied from the c/inically, radiologically, pathologically and inmunologically. The characteristic of systemic rheumatoid arthritis and systemic lupus erithemathosis are similar in sorne patients, however those with the first disease do have much more severe and destructive articular changes as well as higher titers of rheumatoid factors, on the other hand those with systemic lupus have compromise of the kidneys with much more frequency and a/so higher antinuclear antibodies titer in serum. Systemic rheumatoid arthritis would be a bridge between the classical rheumatoid disease and systemic lupus. Positive antinuclear antibodies were found in the serum of sixteen patients and just in fourteen ones in synovial fluids. lt was frecuently found more than one antinuclear antibody pattern. The pheriferal and the specklel antinuclea...