The research has been aimed at developing educational software Q-Box as interactive teaching tool to improve strategic learning biology students in the fourth grade of secondary education in the !E "Manuel Segundo Velasquez Eagle" - Rioja. The hypothesis was formulated on the assumption that the application of QBox Educational software, significantly improve strategic learning of Biology in the fourth grade students of secondary education in the lE "Manuel Segundo Veiasquez Eagien - Rioja. The variabies are organized into two independent variable, represented by Education Software Q-Box and dependent variable, regards strategic learning in biology. The study was conducted with 44 students corresponding to the study sample, determined by non-probability sampling, section "B" corresponds to the experimental group and the "C" was the control group. The type was applied research, experimenta...