The research problem was: ¿Will the educational intervention improve knowledge about puerperal self-care in puerperal women attended at the Maternity Service of the Regional Hospital of Loreto Iquitos 2021?. The objective was to determine the effect of an educational intervention on knowledge about puerperal self-care in puerperal women attended in the Maternity Service of the Regional Hospital of Loreto de Iquitos 2021. The method was quantitative, the quasi-experimental design type pre and post test, the population was made up of 520 puerperal women attended in the Maternity Service of the Regional Hospital of Iquitos, the sample was 30 postpartum women. The techniques were the interview and the educational session, and the instruments were the knowledge questionnaire on puerperal self-care (Cronbach's Alpha reliability of α = 0.93 and validity r= 0.95), and the educational intervent...