Natural toxicological activity such as pinion cake is to reduce environmental and socio-economic impact on human health, compared with synthetic. As to the application of natural toxic is important to understand and correctly identify all the insects on a plantation because they are not all bad for farming, but instead many work as a biological control against harmful insect. Natural pesticides are not of great interest for agribusiness because mass production is not always standardized. Different mixtures tests performed vary in proportion toxicological so many toxicology tests are needed to determine its entirety and proper formulation can be given, what makes this industry is not always profitable. In terms of profitability is important to know the production process knowing that "a toxic can be extracted in various ways, in the case of this research, the technique of dynamic macerati...