El carcinoma cutáneo de células de Merkel es una neoplasia dérmica rara. Debido a su agresividad y muy desfavorable pronostico, requiere de un pronto diagnostico histopatológico, que incluya diagnostico inmunohistoquímico y posteriormente un enfoque terapéutico multimodal que es esencial para un adecuado tratamiento. Se presenta 3 casos de carcinoma de células de Merkel diagnosticados en el laboratorio de Anatomía Patológica de la clínica Ricardo Palma   DOI: https://doi.org/10.25176/RFMH.v17.n2.843

Condyloma acuminatum is a sexually transmitted disease caused by the papilloma virus(HPV) It is frequently found in the ano-genital region and is uncommon in the oral cavity.However, the increase in oral sexual activity has further favored the appearance of HPV in theoral mucosa. This report describes a condyloma in the oral cavity (tongue) of a 43-year-old man withhistory of oral sexual practice, whose diagnosis was confirmed by a biopsy.   DOI 10.25176/RFMH.v19.n1.1799

50 cases of adenomatous hiperplasia of endocervix are reported in 500 cervical biopsy. The rate average was 47 year old. The main symptom was uterine bleeding. Predominant clinic diagnosis was fibroma, and anatomy pathologycal diagnosis were: Adenomyosis, leiomioma, atrophy endometrium, proliferative phase, secretory phase and adenomatous hiperplasia in that order. A high hormonal strogenic factor is suggested as probable etiophatogenic in postmenopause, multipara women. It is important to avoid the misdiagnosis microscopically with adenocarcinoma well differentiated since this reaction is invariably benign.

El carcinoma cutáneo de células de Merkel es una neoplasia dérmica rara. Debido a su agresividad y muy desfavorable pronostico, requiere de un pronto diagnostico histopatológico, que incluya diagnostico inmunohistoquímico y posteriormente un enfoque terapéutico multimodal que es esencial para un adecuado tratamiento. Se presenta 3 casos de carcinoma de células de Merkel diagnosticados en el laboratorio de Anatomía Patológica de la clínica Ricardo Palma   DOI: https://doi.org/10.25176/RFMH.v17.n2.843

El condiloma acuminado es una enfermedad de transmisión sexual causada por el virus del papiloma(VPH). Se encuentra con frecuencia en la región ano-genital y es poco frecuente en la cavidad bucal.Sin embargo, el aumento de la actividad sexual oral ha favorecido aún más la aparición de PVH en lamucosa oral. Este informe describe un condiloma en la cavidad oral (lengua) de un hombre de 43 años conantecedentes de práctica sexual oral, cuyo diagnóstico se confirmó mediante una biopsia.   DOI 10.25176/RFMH.v19.n1.1799

734 intrahospital autopsies of children less than one year old were under research during the 1969-1978 period. The rate average mortality was 44,86 per thousand. The postneonatal component at the end of the last decade decreassed slightly. The premature neonatal component was the mos frequent cause of mortality followed by the neonatal and the late component. The primary causes of mortality in the neonatal period were lung infections (pneumonía), infection of the alimentary tract (enterocolitis), bran haemorrhage, diffuse pulmonary haemorrhage and hialine membrane in that order. In the postneonatal period, the primary causes of mortality were infections of the alimentary tract (enterocolitis) malnutrition, meningoencephalitis, lung infection (pneumonía) and brain haemorrhage. 

734 intrahospital autopsies of children less than one year old were under research during the 1969-1978 period. The rate average mortality was 44,86 per thousand. The postneonatal component at the end of the last decade decreassed slightly. The premature neonatal component was the mos frequent cause of mortality followed by the neonatal and the late component. The primary causes of mortality in the neonatal period were lung infections (pneumonía), infection of the alimentary tract (enterocolitis), bran haemorrhage, diffuse pulmonary haemorrhage and hialine membrane in that order. In the postneonatal period, the primary causes of mortality were infections of the alimentary tract (enterocolitis) malnutrition, meningoencephalitis, lung infection (pneumonía) and brain haemorrhage.