Objective: To determine the clinical, laboratory and epidemiological factors that motivate hospitalization for asthmatic crisis at Yanahuara Hospital, Arequipa-Peru. Material and methods: Observational, prospective, case-control study in which risk factors for hospitalization were studied, comparing 84 hospitalized asthmatic children with 110 control children of the Asthma Program. Results: The highest frequency of hospitalization occurs in the range of 6-12 year-old (51.2 %) majority male (56 %). The associated clinical factors were the fact of presenting previous respiratory symptoms (p<0.01), history of allergic rhinitis (p<0.01; OR=3.80) and history of exercise intolerance (EIB) (p<0.01; OR=4.89). Among the laboratory factors, high IgE was found positive for age (p=0.037; OR=2.70). The epidemiological factors that were associated with ...