Introduction. Alport syndrome is a heterozygous alteration that affects the alpha chains of type IV collagen, manifesting itself clinically in a variable manner, mainly by persistent hematuria. There are different clinical manifestations in this pathology, fnding cases of chronic renal disease. It is crucial to establish measures that allow timely detection, thus reducing complications. Objective. To describe the relationship and importance between Alport syndrome and renal alterations, highlight the clinical manifestations and therapeutic management. Methods. A literature search was performed in PubMed and Scielo databases oriented towards updated and relevant articles in English or Spanish published in the last 5 years. The relationship betweenAlport syndrome and renal pathology was evaluated to describe clinicalsignifcance, diagnosis and treatment. Results. Different studies show a di...

 We present the case of a male patient with no significant pathological history, who experienced abdominal pain radiating to the genital area. An incidental diagnosis of spontaneous venous thrombosis in the epigastric vein, extending to the scrotal vein, was made via Doppler ultrasound. The patient subsequently required anticoagulant therapy. Thromboembolic disease is a condition associated with cardiovascular complications, and its etiology is multifactorial. Doppler ultrasound was the diagnostic method of choice. This report describes a patientwith no relevant medical history, presenting with nonspecific abdominal pain and findings of thrombosis in the epigastric vein, extending to the scrotal vein. Complementary studies revealed elevated lupus anticoagulant levels, which supports the inclusion of this pathology in the differential diagnosis of abdominal pain.