As there is a worldwide adoption of 3D printing (3DP) in many activity areas, formal education becomes mandatory for acquiring theoretical knowledge and hands-on skills for an efficient use, for bringing real contributions to the development of this technology and its applications. Truly digitally natives, Gen Z students are now entering higher forms of education. They are trained by Gen X and early Gen Y professors who should be able to cope not only with students’ different set of skills and mind-set, but also, in case of 3D printing, with the media overexposure of this technology and, consequently, with a tendency of fast acquiring shallow knowledge and being auto-sufficient with this. In this context, our research examines the challenges and implications raised by 3DP curriculum aspects, providing a series of considerations and analyses based on literature review and on a long expe...