Introduction: Anaplastic Large T cells Lymphoma is a rare pathology, determined by expression of CD30 and differences in presentation and aggressiveness according to the ALK expression. Objectives: This study seeks to determine the epidemiological, clinicopathological and prognosis of patients with Anaplastic Large T-cell Lymphoma. Methods: The clinical records of patients diagnosed with Anaplastic Large T cells Lymphoma from the National Institute of Neoplastic Diseases in Lima-Peru were analyzed between years 2006 to 2016. Results: Of 86 patients, 57% were male, 21.9% were positive for ALK, 48 patients were found in clinical stage I and II and 36 between stages III and IV. 57 patients had low or low intermediate risk while 26 patients were between high and high intermediate risk. The estimated overall survival was 40.8% at 5 years. In patients with positive ALK group was 67.4% and in t...

Colorectal cancer (CRC) is the second most frequent cause of direct cancer death worldwide. The study of the molecular state of oncogenes has predictive and prognostic value in metastatic CRC (mCRC). The B-raf proto-oncogene (BRAF) gene mutation represents the 8%-12% of all mutations in mCRC. The BRAF V600E mutation, considered the most common alteration of BRAF, corresponds to a constitutive kinase with a high activating capacity of the RAS/RAF/MEK/ERK pathway after a cascade of successive phosphorylations in the transcription of genes. BRAF V600E mutation is more prevalent in women, elderly, right-sided colon cancer and Caucasian population. Unfortunately, it is considered a poor predictive and prognosis biomarker. Patients with mCRC BRAF V600E mutated (BRAFm) are generally associated with poor response to chemotherapy and short progression-free survival and overall survival. Recently,...

Background: Gastric cancer (GC) is the fourth most common cause of cancer deaths around the world and the first cause of cancer deaths in Peru