Objective: To assess the role of brain magnetic resonance imaging (MRI) in fetusespresenting with isolated ventriculomegaly (IVM) in the ultrasound (US) evaluationof the fetal brain. Methods: US and MRI findings of 197 fetuses diagnosed withIVM between November 2018 and November 2020 were retrospectively evaluated.Fetuses with abnormal karyotypes, additional anomalies, or known etiologies forventriculomegaly were excluded. US and MRI findings were compared both in termsof mean ventricular measurements and IVM grade. Results: MRI measurementswere significantly higher in mild IMV (10.33 ± 0.38 mm vs. 11.11 ± 0.51 mm, p<0.001) compared to US. In mild IVM, MRI measured ventricles larger than US witha mean difference of 0.78 mm. There was no significant difference in US and MRImeasurements in terms of mean values in moderate and severe IVM. There wasgood agreement between US and MRI in d...

Intrahepatic cholestasis of pregnancy (ICP) leads to adverse perinatal outcomes and these outcomes are affected by high total bile acid (TBA) levels. Studies have shown that thyroid hormones regulate bile acid metabolism. However, few studies have evaluated the role of thyroid hormones in ICP. Objective: To evaluate thyroid function along with TBA levels in ICP. Methods: In this retrospective study, 252 pregnant women, including 126 ICP and 126 controls, were evaluated. Third trimester TBA, thyroid-stimulating hormone (TSH), and free thyroxine (fT4) levels of all pregnant women were assessed. Correlation between TBA and fT4, TSH levels were examined. In addition, the perinatal outcomes of both groups were determined. Results: fT4 levels were significantly higher in ICP. There was also a positive correlation between fT4 and TBA levels. TSH levels were similar in both groups and there was ...

Background: The effect of subclinical hypothyroidism (SCH) on adverse perinataloutcomes is unclear, and thyroid-stimulating hormone (TSH) reference values inpregnancy are controversial. Objective: To evaluate the effects of thyroid peroxidaseantibody (TPOAbs) negative SCH on perinatal outcomes according to the differentTSH reference values. Methods: A total of 554 pregnant women, including 509euthyroid and 45 subclinical hypothyroid (TSH > 3 mIU/L) pregnant women, wereincluded in this prospective case-controlled study. All pregnant women were inthe third trimester and were TPOAbs negative. Thyroid functions were evaluatedusing trimester-specific reference values recommended by the American Collegeof Obstetrics and Gynecology (ACOG) (TSH > 3 mIU/L) and the American ThyroidAssociation (ATA) (TSH ≥ 4 mIU/L) guidelines. Results: Neonatal mortality insubclinical hypothyroidism with a ...

Introduction: Fetal cardiac tumors are rare and generally have a good prognosisdepending on location and size. Objective: To examine perinatal and postnataloutcomes along with ultrasound and genetic findings of fetal cardiac rhabdomyoma.Methods: This retrospective cohort study was conducted in a single tertiary center.Ten prenatally diagnosed cases of fetal cardiac rhabdomyoma were included inthe study. The data obtained included maternal characteristics, gestational age atdiagnosis, echocardiographic features including tumor size, number and location,other antenatal ultrasound findings, genetic and pathological examinations,gestational age at birth, neonatal outcomes, and postnatal long-term outcomes.Results: In half of the cases (five), multiple tumors were detected sonographically.Tumor sizes ranged from 5 to 38 millimeters (mm). Four (40%) of the cases hadadditional cardiac anomalies...