Objective. To determine the amount of counterfeit drugs admitted to the National Center for Quality Control of the National Institute of Health during the period 2015-2019 and the socioeconomic and public health consequences in our society. Methods. The analysis of the information collected corresponds to counterfeit medicines. This information was processed in a structured spreadsheet with the necessary parameters. Results. Counterfeit medicines in relation to the total medicines analyzed were: 5.7; 7.2; 4.9; 17.0 and 13.3% in 2015, 2016, 2017, 2018 and 2019 respectively. Of 547 counterfeit medicines, according to the ATC Classification, the following therapeutic subgroups stand out: anti-inflammatory and antirheumatic products (22.1%) and antibacterials for systemic use (16.5%). The predominant form of counterfeiting was medicines without an active ingredient (38.6%), followed by those...