Nowadays, cancer is one of the main causes of death worldwide, the cure of which makes it one of the most important targets of modern medicine. Conventional therapies are, either highly invasive (surgery) or little selective (chemo- and radiotherapy), which diminishes the effectiveness of these treatments leading to undesired secondary effects. Nanomaterials, due to its nano size, possess new special features that may provide several advantages for the diagnosis and treatment of this disease in all of its forms. These new systems, have great potential for leading to an early detection of cancer and the design of personalized therapies working only at target zones, improving the results obtained.

Nowadays, cancer is one of the main causes of death worldwide, the cure of which makes it one of the most important targets of modern medicine. Conventional therapies are, either highly invasive (surgery) or little selective (chemo- and radiotherapy), which diminishes the effectiveness of these treatments leading to undesired secondary effects. Nanomaterials, due to its nano size, possess new special features that may provide several advantages for the diagnosis and treatment of this disease in all of its forms. These new systems, have great potential for leading to an early detection of cancer and the design of personalized therapies working only at target zones, improving the results obtained.

Nowadays, cancer is one of the main causes of death worldwide, the cure of which makes it one of the most important targets of modern medicine. Conventional therapies are, either highly invasive (surgery) or little selective (chemo- and radiotherapy), which diminishes the effectiveness of these treatments leading to undesired secondary effects. Nanomaterials, due to its nano size, possess new special features that may provide several advantages for the diagnosis and treatment of this disease in all of its forms. These new systems, have great potential for leading to an early detection of cancer and the design of personalized therapies working only at target zones, improving the results obtained.

Objectives: To determine genetic midtrimester amniocentesis outcomes in twin gestations. Design: escriptive retrospective study. Setting: Prenatal Diagnosis Unit, Hospital Universitario Miguel Servet, Instituto Aragones de Ciencias de la Salud, Zaragoza, España. Patients: Women with twin gestations. Methods: Computerized database and medical records of pregnant women attended from January 2004 to February 2008 ere reviewed. Twin pregnancies undergoing amniocentesis were compared with singleton pregnancies also exposed to amniocentesis and with unexposed twin pregnancies. Main outcome measures: Obstetrical and perinatal complications. Results: During the four years study 4 263 amniocentesis were performed, 112 in twin gestations and 4 151 in singleton gestations. Advanced maternal age and anxiety were the most common indications for amniocentesis. Fetal loss within four weeks after the p...

Objectives: To determine genetic midtrimester amniocentesis outcomes in twin gestations. Design: escriptive retrospective study. Setting: Prenatal Diagnosis Unit, Hospital Universitario Miguel Servet, Instituto Aragones de Ciencias de la Salud, Zaragoza, España. Patients: Women with twin gestations. Methods: Computerized database and medical records of pregnant women attended from January 2004 to February 2008 ere reviewed. Twin pregnancies undergoing amniocentesis were compared with singleton pregnancies also exposed to amniocentesis and with unexposed twin pregnancies. Main outcome measures: Obstetrical and perinatal complications. Results: During the four years study 4 263 amniocentesis were performed, 112 in twin gestations and 4 151 in singleton gestations. Advanced maternal age and anxiety were the most common indications for amniocentesis. Fetal loss within four weeks after the p...