Recently there are models that study the hydrological behavior in the land cover of the hydrographic basins. For this reason, it is essential to understand the hydrological impact on land cover, which will serve for the management of watersheds. The study analyzed the changes in plant cover for the periods between 1985 and 2015, where plant covers such as Tolar, Wetlands, Puna grassland, Andean grasslands, and Yaretales were identified. Therefore, it was shown that there are losses of soil covers such as wetlands at 2.39%, Puna grassland at 1.71%, and Andean grassland at 4.77%. In addition, in this research, the semi-distributed model of Soil and Water Assessment (SWAT) was applied to study the impact of land use and land cover change (LULC) on the basin's water balance under study. The model was calibrated from (1981-1992), with the flow data observed. The result indicates that the most...