The aim of this study was to compare the effect of the application of a flowable resin composite coating, over a collagen sponge stabilized with suture, on postoperative pain after free gingival graft harvesting. Thirty-two free gingival grafts were harvested from the palate in 32 patients, who were subsequently randomized to have only a collagen sponge stabilized with sutures applied to the palatal wound (control), or to have the collagen sponge coated with a flowable resin composite (test). Patients were observed for 14 days, and the pain level was evaluated by using a numerical rating scale. The consumption of analgesics during the postoperative period and the characteristic of the graft were also analyzed. The patients in the test group reported having experienced significantly less pain statistically than the patients in the control group throughout the study. The consumption of ana...

Objetivos: Determinar las manifestaciones bucales en pacientes con insufi ciencia renal crónica en hemodiálisis del Hospital Alberto Sabogal Sologuren (Bellavista, Callao, Perú) en el periodo de julio-agosto 2013. Materiales y Métodos: Se examinaron a 119 pacientes de ambos sexos. Se les realizó una anamnesis y luego con la ayuda de una linterna, espejos bucales y baja lenguas se les examinó la cavidad bucal de manera minuciosa. Resultados: Los pacientes examinados presentaron lengua saburral 88,2%, agrandamiento gingival 63%, sangrado gingival55,5%, caries dental 85,7%, cálculo dental 80,7%, perdida de inserción dental 72,3%, xerostomía 84%, halitosis 66,4% y disgeusia 55,5%. Se estudió la relación de las manifestaciones bucales según el tiempo de hemodiálisis, encontrándose que existió una asociación estadísticamente signifi cativa en la mayoría de las lesiones (prueb...

Objective: This systematic review evaluates the effect of laser gingivectomy on the improvement of periodontal health parameters in patients with gingival enlargement due to fixed orthodontic appliances. Materials and methods: A systematic review was conducted in 3 databases without language or date restrictions. Clinical trials involving patients with gingival enlargement (GE) or hyperplasia induced by fixed orthodontic treatment and treated by laser gingivectomy, conventional surgery (scalpel) or non-surgical periodontal treatment (NSPT) were included regarding periodontal parameters such as bleeding on probing, probing depth, gingival inflammation, among others. Results: From the 363 articles initially retrieved, only 6 were included after evaluation of the full text. However, all studies were considered to have a high risk of bias. It was detected that periodontal parameters (bleedin...

Objective: To compare the clinical outcomes of the tunnel technique (TUN) combined with either thin connective tissue graft (CTG) (TUN + thin CTG) (1 mm) or thick CTG (TUN + thick CTG) (2 mm) for the treatment of localized gingival recession (GR). Material and methods: Twelve patients, with 24 maxillary localized type RT1 GR were randomly assigned into two groups. Clinical, esthetic, and patient‐reported outcomes were evaluated at baseline and at 6-month follow-up. Results: The TUN + thin CTG group showed a higher mean GR reduction (1.53 ± 0.66) (primary outcome variable) than the TUN + thick CTG group (1.44 ± 0.89), but no statistically significant difference was detected at the 6-month follow-up (p = 0.77). No statistically significant differences were found between TUN + thin CTG and TUN + thick CTG concerning complete root coverage (CRC) (58.3% versus 41.7%, respectively), gingiv...

The development of extracellular vesicles (EVs) therapies has revolutionized personalized medicine, opening up new possibilities for treatment. EVs have emerged as a promising therapeutic tool within this field due to their crucial role in intercellular communication across various cell types and organisms. This systematic review aims to evaluate the therapeutic potential of oral mesenchymal stem cell (MSC)-derived EVs for bone regeneration, specifically focusing on findings from preclinical models. Sixteen articles meeting the inclusion criteria were selected following document analysis. The biological effects of oral MSC-derived EVs predominantly involve the upregulation of proteins associated with angiogenesis, and inflammation resolution, alongside the downregulation of proinflammatory cytokines. Moreover, these therapeutic agents have been found to contain a significant quantity of ...