Clinopodium brevicalyx grows in the southern high Andean regions of Peru and has wide popular use, however to date there is no research on its activity against Trichophyton rubrum, an anthropophilic dermatophyte fungus with an affinity for human keratin and difficult to treat, causing the most common superficial mycoses such as athlete's foot, ringworm and nail infections. The aim of this research was to determine the activity of the essential oil of Clinopodium brevicalyx against Trichophyton rubrum ATCC 28188. The essential oil was obtained by hydrodistillation, the extraction rate was 1.98 ± 0.02% (w/v), and the physicochemical characteristics were: relative density of 0.93654 g/mL, a refractive index of 1.4625, an optical rotation of 2.14°, and pH of 6.20. The chemical composition of the essential oil was determined using a gas chromatograph coupled to a mass spectrometer, identify...

Clinopodium brevicalyx grows in the southern high Andean regions of Peru and has wide popular use, however to date there is no research on its activity against Trichophyton rubrum, an anthropophilic dermatophyte fungus with an affinity for human keratin and difficult to treat, causing the most common superficial mycoses such as athlete's foot, ringworm and nail infections. The aim of this research was to determine the activity of the essential oil of Clinopodium brevicalyx against Trichophyton rubrum ATCC 28188. The essential oil was obtained by hydrodistillation, the extraction rate was 1.98 ± 0.02% (w/v), and the physicochemical characteristics were: relative density of 0.93654 g/mL, a refractive index of 1.4625, an optical rotation of 2.14°, and pH of 6.20. The chemical composition of the essential oil was determined using a gas chromatograph coupled to a mass spectrometer, identify...

Las dermatofitosis constituyen las micosis superficiales más frecuentes en todo el mundo, dentro de la dermatofitosis el agente etiológico con mayor frecuencia aislado es Trichophyton rubrum, responsables de infecciones comunes y de difícil tratamiento; genera desde incomodidad hasta convertirse en un problema grave cuando accede a circulación sistémica. El objetivo de esta investigación fue evaluar la actividad antimicótica in vitro del aceite esencial de las hojas de Clinopodium brevicalyx “Cjuñuca” mediante los métodos de difusión en disco y macrodilución, y realizar una formulación farmacéutica a base del aceite esencial en estudio, frente a cepas ATCC de Trichophyton rubrum. La actividad antimicótica se evaluó mediante dos métodos: Difusión de discos, las concentraciones de aceite esencial fueron 10, 20, 30, 50, 100, 150, 250 y 500 μL / mL, como control positiv...

Clinopodium brevicalyx grows in the southern high Andean regions of Peru and has wide popular use, however to date there is no research on its activity against Trichophyton rubrum, an anthropophilic dermatophyte fungus with an affinity for human keratin and difficult to treat, causing the most common superficial mycoses such as athlete's foot, ringworm and nail infections. The aim of this research was to determine the activity of the essential oil of Clinopodium brevicalyx against Trichophyton rubrum ATCC 28188. The essential oil was obtained by hydrodistillation, the extraction rate was 1.98 ± 0.02% (w/v), and the physicochemical characteristics were: relative density of 0.93654 g/mL, a refractive index of 1.4625, an optical rotation of 2.14°, and pH of 6.20. The chemical composition of the essential oil was determined using a gas chromatograph coupled to a mass spectrometer, identify...

Clinopodium brevicalyx grows in the southern high Andean regions of Peru and has wide popular use, however to date there is no research on its activity against Trichophyton rubrum, an anthropophilic dermatophyte fungus with an affinity for human keratin and difficult to treat, causing the most common superficial mycoses such as athlete's foot, ringworm and nail infections. The aim of this research was to determine the activity of the essential oil of Clinopodium brevicalyx against Trichophyton rubrum ATCC 28188. The essential oil was obtained by hydrodistillation, the extraction rate was 1.98 ± 0.02% (w/v), and the physicochemical characteristics were: relative density of 0.93654 g/mL, a refractive index of 1.4625, an optical rotation of 2.14°, and pH of 6.20. The chemical composition of the essential oil was determined using a gas chromatograph coupled to a mass spectrometer, identify...