Waste management in cities has proved to be a complex task for policy-makers who seek cost reductions when taking decisions. However, on many occasions substantial environmental gain can be attained through waste management optimization. In this particular study, the main objective was to combine operational research techniques with Life Cycle Assessment to locate collection sites for general and recyclable residues and create an effective collection-route system for compactor trucks to attain a reduction in environmental impacts. The case study selected was the district of Comas, one of the most populated districts in the city of Lima, a city that has experienced several episodes of poor waste collection management in recent years. For the location of the collection sites a mathematical optimization model was proposed to decide where to locate them, as well as the number of containers r...