Machine learning is widely used in the medical field and is increasing more and more because of the amount of data stored. The results obtained by the predictive models serve as support for good decision-making for medical personnel. The objective was to identify which methods, variables, and models are used for the prediction of arterial hypertension using machine learning. The systematic review was carried out in the PubMed, ScienceDirect, Redalyc and Scopus search engines, studies referring to the prediction of early diagnosis of arterial hypertension in people. For the selection process, Prisma was used, applying different exclusion criteria. 10,916 articles were found, 15 being included for the review. Several authors apply more than one model to compare the results in their research. The model most mentioned, used and with the best result was Random Forest, obtaining a Specificity ...