Resultados de Búsqueda por Autor

artículo

Access to Methotrexate Monitoring in Latin America: A Multicountry Survey of Supportive Care Capacity

Publicado por
Villanueva, G, Lowe, J, Tentoni, N, Taluja, A, Villarroel, M, Narváez, CE, León, SA, Valencia, Libreros, DL, Gonzalez, Suárez, N, Mikkelsen, TS, Howard, SC

Publicado 2024

Enlace

High-dose methotrexate (HDMTX) is used to treat a broad spectrum of cancers. Methotrexate (MTX) monitoring and adequate supportive care are critical for safe drug administration; however, MTX level timing is not always possible in low- and middle-income countries. The aim of this study was to evaluate HDMTX supportive care capacity and MTX monitoring practices in Latin America (LATAM) to identify gaps and opportunities for improvement. A multicenter survey was conducted among LATAM pediatric oncologists. Twenty healthcare providers from 20 institutions answered the online questionnaire. HDMTX was used to treat acute lymphoblastic leukemia (ALL; 100%), non-Hodgkin lymphoma (84.2%), diffuse large B-cell lymphoma (47.4%), osteosarcoma (78.9%), and medulloblastoma (31.6%). Delays in starting HDMTX infusion were related to bed shortages (47.4%) and MTX shortages (21.1%). MTX monitoring was pe...

artículo

International Society of Paediatric Oncology (SIOP) Global Mapping Program: Analysis of healthcare centers in countries of the Latin American Society of Pediatric Oncology (SLAOP)

Publicado por
Gorostegui-Obanos, M, Chantada, L, Filho, NPC, Gonzalez-Ramella, O, Serrano, B, MJ, Valencia, D, Sampor, C, Macedo, C, Ramirez, O, Sardinas, S, Lezcano, E, Calderón, P, Gamboa, Y, Fu, L, Gómez, W, Schelotto, M, Ugaz, C, Lobos, P, Moreno, K, Palma, J, Sánchez, G, Moschella, F, Gassant, PYH, Velasquez, T, Quintero, K, Forteza, M, Villarroel, M, Moreno, F, Alabi, SF, Vasquez, L, Lowe, J, Cappellano, A, Challinor, J, Chantada, GL

Publicado 2024

Enlace

Background: The International Society of Paediatric Oncology Society Global Mapping Program aims to describe the local pediatric oncology capacities. Here, we report the data from Latin America. Methods: A 10-question survey was distributed among chairs of pediatric oncology services. Centers were classified according to patient volume into high- (HVC; 100 or more new cases per year), medium- (MVC; 31–99 cases), and low-volume centers (LVC; 30 cases or less), respectively. National referral centers (NRC) were identified. Results: Total 307 centers in 20 countries were identified (271 responded), and 264 responses were evaluable, accounting for 78% of the expected cases (21,359 cases per year). Seventy-seven percent of patients are treated in public centers, including additional support by civil society organizations. We found that 66% of the patients are treated in 70 centers of excell...