Studies of drug use have become a useful tool to identify patterns, profiles and other features of use in clinical practice of medicine and especially of antimicrobials are tool whose misuse is leading to increased resistance antibacterial. In this paper we have made a study of the evolution of consumption of antimicrobial booking as vancomycin, in order to provide information about how it has evolved this antibiotic consumption in hospitals during the period 2012-2014 . An observational descriptive study was conducted retrospective. ATC / DDD methodology for calculating consumption 500mg vancomycin was used. services in medicine, surgery, ICU and NICU and the consumption value expressed in soles was calculated consumption trends over time and the correlation between variables were established using the linear regression analysis, it is accepted as a criterion for significance the value ...