Background: The finding of short femur (length below the 5th centile) at second trimester ultrasound examination is a diagnostic challenge. Classically, the short femur has been associated to chromosomal abnormalities and skeletal dysplasias. A few reports have been published on fetuses with isolated short femur outcomes. Objectives: To determine perinatal outcomes in the second-trimester fetuses with isolated short femur and to determine its association with fetal growth restriction. Design: Retrospective cohort study, also called historical or concurrent study. Setting: Fetal Medicine Unit, Instituto Nacional Materno Perinatal, Lima, Peru. Participants: Women with 16 to 28 weeks pregnancies. Interventions: The sample size was drawn from our 2006-2008 databases and consisted in 278 fetuses 16 to 28 weeks who had ultrasound examination. We categorized two groups: fetuses with isolated sh...

Background: The finding of short femur (length below the 5th centile) at second trimester ultrasound examination is a diagnostic challenge. Classically, the short femur has been associated to chromosomal abnormalities and skeletal dysplasias. A few reports have been published on fetuses with isolated short femur outcomes. Objectives: To determine perinatal outcomes in the second-trimester fetuses with isolated short femur and to determine its association with fetal growth restriction. Design: Retrospective cohort study, also called historical or concurrent study. Setting: Fetal Medicine Unit, Instituto Nacional Materno Perinatal, Lima, Peru. Participants: Women with 16 to 28 weeks pregnancies. Interventions: The sample size was drawn from our 2006-2008 databases and consisted in 278 fetuses 16 to 28 weeks who had ultrasound examination. We categorized two groups: fetuses with isolated sh...