Low-grade neuroepithelial tumors (LGNET) are a diverse group of neoplasms occurring most commonly in children and young adults, often associated with epilepsy and favorable clinical outcomes. They are composed of a spectrum of tumor entities with divergent clinicopathologic features including ganglioglioma, pilocytic astrocytoma, dysembryoplastic neuroepithelial tumor (DNT), rosette-forming glioneuronal tumor (RGNT), extraventricular neurocytoma (EVN), multinodular and vacuolating neuronal tumor (MVNT), polymorphous low-grade neuroepithelial tumor of the young (PLTNY), myxoid glioneuronal tumor (MGNT), diffuse leptomeningeal glioneuronal tumor (DLGNT), and papillary glioneuronal tumor (PGNT). However, histologically distinguishing between these different LGNET subtypes can be challenging, and molecular profiling is now recognized as critical for accurate classification. While some LGNET ...