1
tesis de grado
Publicado 2010
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This research aims at realizing the "Chemical composition analysis of fresh milk coming from mothers clubs social program of Vaso de Leche of the Provincial Municipality of Trujillo from of May to June 2010" and to verify if it complies with the quality standards parameters established in the Peruvian Technical Standard PTS 202.001:2010, which was used for 840 samples, each one of 250 mL, from 70 mothers clubs. To achieve the research objective physical – chemical tests and organoleptic features were performed complying with the provisions of the PTS with respect to density, acidity, protein, fat, dry extract, non-fatty extract, alteration test 97; 96,31; 95,80; 97,62; 91,70; 97,14; 98,20 per cent respectively and adulteration test negative
2
tesis de grado
Publicado 2009
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The goal of this study was to compare de dissolution profile of Diazepan in both generic Lab Farmindustria and VALIUM Lab Roche 10 mg- tablets. Whit this in mind, characterization of the dissolution profiles for both formulation was performed into three medium: HCl 0.1N pH 1.2, Acetate Buffer pH 4.5, and Phosphate buffer pH 6.8, according to the bioequivalency in vitro studies established by OMS. Dissolution profiles were analysed following zero-order, first-order, cube root, Higuchi’s, Weibull’s and similarity factor (f2) models. The first-order kinetic model and Weibull function best characterized of the dissolution profiles of both presentations. The dissolution rate constants of both formulations were similar at pH 1.2, 0.19019 min-1 for VALIUM ® and 0.16641 min-1 for generic Diazepam (p> 0.05), and factor analysis of similarity factor gave values below the range in the three me...