This study uses multiple ground and satellite-based measurements to investigate the extreme ionospheric response to the Mother's Day storm on May 10–11, 2024. Prompt penetration electric field caused a significant enhancement in the ionospheric vertical drift (∼ 95 m/s) and the equatorial electrojet strength (∼ 275 nT) over Jicamarca. These extreme eastward electric field perturbations, along with the large meridional wind, significantly altered the F-region plasma fountain at different local times. The afternoon equatorial ionization anomaly (EIA) not only sustained for an exceptionally long duration (∼12 hr) but also expanded spatially over time. The separation between the two peaks of EIA crests exceeded ∼48° and ∼70° in the morning and evening sectors, respectively. This study shows, for the first time, that unusually strong EIA can not only develop at different local t...