The central granular cell odontogenic tumor (CGCOT) is a rarely seen neoplasm of odontogenic origin with a predilection for mandible of middle aged women. The lesion shows slow growing and radiographic feature of a radiolucent unilocular lesion with a radiopaque border. The present study aims to report a new case of CGCOT with an atypical involvement of anterior maxilla. Clinical exam showed swelling of the hard palate and the vestibular area of left canine and pre-molar of maxilla. Cone beam computed tomography showed a hypodense unilocular well delimited lesion extending from central left incisive to left pre-molar region. Histopathological analysis showed granular eosinophilic cells and islands of odontogenic epithelium and positive immunostaining for CK14, vimentin, CD68, Ki67 and S-100, which established the diagnosis of CGCOT. The patient is under follow-up without recurrence for s...

Actinomycosis is a rare chronic suppurative infection that affects upper airways and the gastrointestinal tract. The aim of this work was to review important information regarding the etiopathogenesis, clinical features and treatment of cervicofacial actinomycosis. According to the anatomic site affected, it is classified into three clinical forms: cervicofacial (50%), thoracic (30%) and abdominal (20%). We present here a literature review focusing on important aspects of cervicofacial actinomycosis. Despite the name comprising the term mycosis, the disease is caused by Gram-positive bacteria of the genus Actinomyces, mainly Actinomyces israelii, which are commensals of the oral microbiota. Nevertheless, when the integrity of the oral mucosa is compromised, they can become pathogenic. Actinomycosis evolves slowly and it often mimics other clinical conditions such as malignancies. Treatme...