We report two cases of extragonadal pelvic endodermal sinus tumor diagnosed at the Departament of Pediatric of the National Institute of Neoplastic Diseases and discuss the clinical presentation, differential diagnosis and pathologic study.

We report a case of a seven year old girl, from Parinas-Piura, who was admited in the Instituto Nacional de Enfermedades Neoplasicas with an expansile intracraneal process and neurological deficit. The patient die and the necropsy shown osteomyelitis of right orbital bones and chronic meningoencephalitis with angiitis due to free living amoebas.