The toxicity of the aqueous extract of Stevia rebaudiana in Rattus norvegicus variety Sprague Dawley was evaluated for 60 days. It was held at the Biology Biology UNSA, Arequipa, during the months August to December 2012 16 Rattus norvegicus Sprague Dawley variety distributed in four groups of 4 rats each were used: The distilled water (Control Group) was administered to the control group, the Stevia rebaudiana aqueous extract was administered to the orogastric group experimentally 2, 3, 4 doses of 0.3, 0.6 and 0.9 g / kg / day respectively. Wierner's kits were used for the determination of TGO, TGP, glucose and creatinine. Body weight was measured on an Omni 5300 digital scale. The tissues evaluated (liver, kidney and stomach) by the Harris method. There was no significant difference in the activity of TGO and TGP in plasma of Rattus norvegicus variety Sprague Dawley with treatment of a...