The aim of this research was to evaluate the effect of alternative natural products in the control of Varroa destructor in honey bees (Apis mellifera) in an apiary located in Sayán, Lima region, Peru. Five treatments (oxalic acid, thymol, vaseline, tobacco and control) and six replications per treatment were used for 16 days. The hives with rates greater than 2% of varroa infestation were selected and the evaluations were carried out in the adult bee, operculated cells and floor of the hive at the beginning and end of the experiment. The Proportions Test was used to evaluate the effectiveness of the treatments in adult bees and in operculated cells, while the Kruskall-Wallis test and Dunn's post hoc test were used to evaluate dead varroa on the hive floor. When comparing the level of infestation at the beginning (day 0) and at the end of the experiment (day 16), oxalic acid, thymol and ...