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 The objective was to determine the relationship between the glycosylated hemoglobin level and the prevalence of type - 1 plasminogen activator inhibitor elevated in type 2 diabetic patients. The type was quantitative, design descriptive and crosssectional, 632 elderly patients were selected. 18 years, 263 men and 369 women diagnosed with type 2 diabetes, analyzed the plasma markers: PAI -1, tPA, fibrinogen and homocysteine. The status of type 2 diabetes was evaluated with HbA1c, considering itself uncontrolled patient with Hb1c values> 5.9%. Among the main results, the group of high type 2 diabetic patients (HbA1c> 5.9%) has a prevalence of 74.4% of elevated PAI-1 while patients with normal HbA1c have a prevalence of 40.7, which means that Patients who do not control their glycemic profile have 3.9 (Odd Ratio) times more risk of presenting high levels of PAI -1 in relation to...