Transient neonatal myasthenia gravis (TNMG) is an acquired autoimmune disease that occurs in10 to 20 % of newborns born to mothers with myasthenia gravis. Symptoms appear within thefirst 24-72 hours and disappear after weeks or months, with 90 % of patients achieving completerecovery by 2 months of age. The typical presentation begins with respiratory distress, generalizedhypotonia, and feeding difficulties, requiring clinical surveillance from birth due to the possibilityof early hospitalization.We present the case of a newborn, born to a mother with myasthenia gravis, who was admittedat 7 days of age to the Intermediate Care Unit of Hospital Nacional Arzobispo Loayza due tohypoactivity, poor sucking and hypotonia. Given the suspicion of TNMG due to the maternalhistory and the patient’s symptoms, a therapeutic anticholinesterase test was performed,showing immediate improvement in spon...