Introduction: Bolton analysis is used to determine anomalies with respect to the dental mass, for diagnosis and treatment planning purposes, the possibility of using a digital method was introduced and tested to measure the size of the mesiodistal tooth. In this way, digital dental technology has made digital study models become popular in orthodontics. Objective: to evaluate the degree of reliability of the evaluation of the Bolton analysis in three-dimensional virtual models versus plaster models through a review of the literature. Materials and methods: A search was carried out in the primary databases of the international scientific literature on health sciences: Medline, through PubMed, SciELO, Lilacs, and Embase. Review articles published between the year 2000 and October 2021 were included. Results: The desktop scanner was the best option for digitizing dental models, but this doe...