The intergenic interval is a determining factor of maternal and fetal morbidity and mortality. It has social, economic and demographic importance. Both the short intergenic period (24 months) and the long intergenic period (60 months) have been involved in adverse effects. Through this investigation, it is expected to find the relationship of the short intergenic interval as a risk factor for the development of preeclampsia. Objective: To determine if the short intergenic interval is a risk factor for the development of preeclampsia in pregnant women. Material and methods: An analytical, observational, case-control study was conducted in the Gynecology-Obstetrics Service of the Teaching Regional Hospital of Trujillo during the period January 2009 - December 2015, which evaluated 96 puerperal women, in which 48 cases were compared. , with 48 controls, to which the short intergenic period ...