ABSTRACT The present study was prospective and comparative study of longitudinal cut which consisted in 72 patients of whom were 21 women,15 men (experimental group) and 25 women, 11 men (control group) attending the Dental Clinic of Moche that required treatments of dental extractions dental simple and complex. Objective: To determine the efficacy of the use of PRF in the healing of alveolus post extraction dental simple and complex in the Dental Clinic of Moche of the National University of Trujillo. Material and method: Inclusion criteria were: People with apparent good general health ASA I, with indication of exodontia simple and complex in parts unirradiculares, multirradiculares and people who accepted to participate in the investigation, by signing the cons ent or settlement informed. The age was < 40 and ≥ 40 there were 36 patients with PRF (two clots and two membranes in each ...