Introduction: The changes in daily routines as a result of the mitigating measures implemented in the face of the COVID-19 pandemic represent a challenge for the Latin American population to preserve their general well-being. Objective: To evaluate the wellness assessment from the lifestyle medicine program Cardiofood Lifestyle in virtual modality in Latin American participants during the COVID-19 pandemic in 2020. Methods: Analytical, retrospective and descriptive study, with a quantitative approach; developed in virtual mode between May and December 2020. The population sample was 51 participants. A subjective assessment questionnaire and a self-authorship wellness score were applied and validated by a hypothesis test. The P value equal to zero is calculated. Results: Of 51 participants, 44 (86%) were women with a mean age of 45 and 7 (14%) were men w...