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1
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In this paper a summary of research conducted by the Institute of Biochemistry and Nutrition, Faculty of Medicine of Lima regarding nutritional problems Peru is made. To this end there have been clinical, haematological and biochemical studies to identify deficiency states in groups of individuals from different economic classes, soldiers, adults, children and seniors. Regarding calorie needs an applicable table shows the average weight in relation to age, obtained from national surveys. Protein deficiencies, the solution would be in the highest consumption of fish are detected. Referring to the lack of calcium in the diets is shown that by the constant action of the solar rays properly manage groups examined using the poor contribution. Alkaline phosphatase determinations reveal absence of rickets. A high percentage of anemia in the jungle due to high intestinal parasitism and overall d...
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The Versed is ethylene diamine acid tetracélico whose corboxílicos groups can be neutralized by cations, becoming the versenatos. If you reach the organism Versenate sodium, extracellular fluid calcium replaces sodium as accomplished Versenate calcium eliminated by the kidney, causing transient hypocalcaemia. Also, if adequate calcium Versenate doses are injected, this cation can be replaced by other metals (lead, copper, mercury, zinc, vanadium. Etc.), property which can be used to remove toxic metals that have managed to settle in organism.
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The serum proteins are presented with constant figures in well-nourished and healthy subjects; hence their concentration is an index of nutritional status and results at the same time the quality and quantity of ingested food proteins because, before the deficiency this contribution a number of clinical processes that culminate mainly occur in growth arrest, and severe in the presence of Kwashiorkor in very young children cases.
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Determination of Vitamin C or ascorbic acid in serum is used for diagnosing the states of serious deficit in food supply, which brings scurvy.
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This time, we present the work done in the city of Tarapoto, influential in the development of eastern Peru and where the work of the "Marginal Road" linking north and south are a number of centralized populated places and then the access roads to the mountains and coast, ensure a means of communication that allow them out of isolation in which they live and the development of agro-livestock activities in the extensive area of high forest. in this way you can have land to house hundreds of thousands of peasants living in subhuman conditions in the mountains and overpopulated coast.
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At the suggestion of my teacher Professor Carlos Monge, I have the honor to participate is this interesting Anthropology Conference. Dedicated exclusively to Biochemistry understood that my historical knowledge is scarce, when they had earned some references from people who have dealt with these issues, particularly those published by Professor Juan B. Lastres, to treat it entirely from the nutritional point of view .
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We have studied the time uropepsina concentration in men and having obtained an average of 32 units and 19 women, all normal. The study of the enzyme in gastric and duodenal ulcers give higher results than the normal average, gastric neoplasms in the figures are low, but as individual variations are large, it is doubtful that this determination can provide clinical utility, replacing tubaje gastric. Studying in gastrectomized uropepsina reveals that partial ulcer or cancer concentration decreases. In the total gastrectomy uropepsina disappears. In anemia with achlorhydria gastric juice enzyme research pays great diagnostic value; in pernicious anemia uropepsina is absent in the other, including aplastic hasy decline. The use of adrenocorticotropic hormone (ACTH) and cortisone in excretion study provides valuable services uropepsina. In normal subjects, administration of 25 mg regimen. of...
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Earlier in this volume Aguilar and Caceres studied from the point of view, chemical and biochemical 100 poor children in Lima, 6 to 14 years old. This paper deals with the study of inorganic phosphorus and alkaline phosphatase in the same children, in order to get an idea of ​​deficiency states of vitamin D, calcium and phosphorus. The average number of inorganic phosphorus is mgrs. 4.78%, 8.76 units of alkaline phosphatase Bodansky, both figures are averages considered normal for children ages indicated. In no case has been found by clinical examination or determination of phosphatases signs of rickets, although the food they receive is poor in calcium. This may be because the subjects studied in school almost entirely properly receive the action of the sun, allowing them to synthesize adequate amounts of vitamin D, which will bring a good use of the little calcium in your diet. The...
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During the Second World War there have been interesting research on the action of 2,3 dimercapto-propanol in poisoning by various substances, both in animals and men, and of particular interest to those of therapeutic use. As work arrived to our hands we have not we found studios with respect to cobalt, which in high doses exerts a toxic action and in small doses can cause polycythemia in various animals, the mechanism until today still remains unclear, we decided to study the effect that the Bal might exist in relation to cobalt. The first results are found regarding this communication.
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Experimental studies have polycythemias dual purpose; First, they can provide useful information for interpreting the other polycythemias mechanism occurring in man; also to better clarify constribuyen erythropoietic function. In our country, flushing height is a problem that deeply interested; production mechanism and implications physiologism have been studied by Professors Monge, Hurtado et al. In our stay in the United States, when we worked in the laboratories of Eleazar Barron, one of the topics we chose as research was polycythaemia caused by cobalt. At the same time we studied the oxidation of ascorbic acid and was discussed on the role of this vitamin in the mechanism of erythropoiesis reason that prompted us to investigate the action that ascorbic acid might exert on the development of polycythemia by cobalt and the study of the intimate mechanism of this polycythemia.
11
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Biological fluids can be divided according to their behavior toward ascorbic acid into two groups: those having an inhibitory mechanism that protects the ascorbic acid oxidation, and those lacking this mechanism. Animal fluids and some of vegetable origin (those containing dosables amounts of ascorbic acid) corresponding to the first group. Ascorbic acid is protected from oxidation in the fluids by the action of copper catalyst. Fluids from plants (those that contain very little ascorbic acid) belong to the second group. Ascorbic acid is oxidized in these fluids by a variety of oxidizing catalysts, copper and hemocromógenos, as evidenced by the effect of inhibitors. The inhibitory effect of glutaction is specific to the catalytic action of ascorbic acid by hemocromógeno ferri-nicotine or yellow pumpkin juice.