The objective of the present investigation was to concurrently validate the manufacturing process of Metformin 850 mg tablets, perform tests on humidity, appearance, bulk density, density per set, hausner index and compressibility, during the mixing phase; tests of appearance, friability, hardness, weight, average weight, and disintegration, during the compression phase. Three batches of 300,000 units each were evaluated, in each batch controls were made in the mixing and compression phase for which the validation of the manufacturing process of Metformin 850 mg tablets was considered; obtaining as a result in the controls in the mixing phase, a conformable appearance, humidity 2.57%, bulk density 0.640 g / mL, good fluidity with respect to the compressibility and hausner index; in the controls of the compression phase, the appearance was conformed, the dimensions were on average 19.1 mm...