Weeds play a significant role in reducing onion production and productivity in Ethiopia. There is limited information on onion weed management in the hot lowland part of the Country. This study evaluates the effectiveness of integrated weed control tactics in onion crops. The treatments were arranged in a randomized complete block design (RCBD) with three replications. The data collected included different weed species, density, and dry weight of weeds, Additionally, onion yield and yield traits had been taken at maturity. The experimental field was infested by grassy and broad-leaved species of weeds including sedge, the predominant weed species. The result of onion yield and yield traits were significantly (p < 0.05) different among treatments. The three-hand hoeing and Pendimethalin 500 SC + Oxyfluorfen 24 EC supported by one-hand weeding on the 70th day after transplant demonstrat...