This paper titled "Comparison of five varieties of lettuce (Lactuca sativa L.) grown under ecological conditions of the Province of Lamas was held in order to evaluate and assess the agronomic performance of five varieties of lettuce (Lactuca sativa L . ) agro-ecological conditions in the province of Lamas, and to conduct economic analysis. The cultivars were: White Boston, Parris !stand Cos, Grand Rapids, Alface venerable, Great Lakes 659 (control), which was used to design randomized complete block (BCCA), with an area of tropical dry forest voda (bs-T) and a soil texture class sandy loam with a slightly acidic pH. Befare planting was carried out biosolarización. The results indicate that the introduced varieties Alface Veneranda and Paris lsland Cos, the higher yields obtained with 17,523 and 16,483 tonnes I ha, variety Grand Rapids, had an intermediate behavior, taking the last plac...