Berberis vulgaris is popularly known as Agracejo in Peru. This species has been shown to have important biological properties such as hypolipidemic, antidiabetic, cholagogue, and hepatoprotective effects. Its effects would be related to the varied phytochemical composition obtained after extraction with different solvents or extraction techniques. Therefore, it is necessary to determine the best extraction conditions to obtain the most significant effects according to each extraction technique used. The objective of this research was to evaluate the effect of ultrasound application on the concentration of total phenols and antioxidant capacity of ethanolic, hydroalcoholic, and aqueous extracts of Berberis vulgaris leaves, extracts were obtained by ultrasound application for 0, 5, 10, 20 and 30 minutes at 40 kHz in an ultrasonic bath. The results indicate that the application of ultrasoun...