Problem statement: Pain is an integral part of the human experience. Therefore, it is important to analyze from Bioethics and its currents of thought the approach to this reality. Objectives: Analyze the phenomenon of pain and suffering based on the different worldviews of Bioethical thought. Materials and Methods: A bibliographic search was carried out from August 2021 to March 2022 using the following search engines: PubMed, EBSCO Host, Web of Science and Scielo. As inclusion criteria: articles that presented a bioethical analysis related to pain management were chosen. As exclusion criteria, all those articles that presented aspects related to pain management or bioethical analysis in an unrelated manner were discarded. Results: The interpretation of pain and its meaning from the different worldviews: liberalism, sociobiologism, utilitarianism and bioethical personalism is crucial, si...