Objective: To perform a literature review on oral squamous cell carcinoma, the presence of cancer stem cells; their association with the course of the disease and therapeutic applications. Methods: A search was performed in the PubMed database by entering the following algorithm: ((((neoplastic stem cells[MeSH Terms]) OR (Cancer stem cells[Text Word])) AND (Squamous Cell Carcinoma of Head and Neck[MeSH Terms])) AND (Oral squamous cell carcinoma[Text Word]), to find articles in english published between 2012 and 2022. The PRISMA diagram was used to identify and select the articles. Results: A result of 49 articles was obtained; of which 27 were chosen according to the title and abstract in their association with the topic. In addition, 8 additional articles suggested by their relationship with the information previously searched were included. In total, 35 articles were evaluated. There h...

Objetivo: Este reporte de caso tuvo como objetivo caracterizar las células primarias del adenoma pleomórfico obtenidas de un tumor de glándula parótida mediante biopsia de tejido, cultivo celular primario y análisis inmunohistoquímico. Métodos: Una muestra de biopsia de tejido de un paciente de 58 años con adenoma pleomórfico se sometió a examen histopatológico y cultivo celular primario. Las células primarias se caracterizaron mediante tinción inmunohistoquímica utilizando anticuerpos contra S-100, SMA, vimentina y citoqueratina AE1/AE3. Además, se tiñeron secciones de tejido embebido en parafina utilizando citoqueratina AE1/AE3, vimentina, calponina, SMA, S100 y p63. Resultados: El cultivo celular primario reveló tinción débil de S-100 y SMA positivo en células mioepiteliales, mientras que vimentina y AE1/AE3 fueron negativas en toda la población celular. En el tej...