Objective: To evaluate the effect of an educational intervention on the prevention and control of malaria in a population from an endemic area of Loreto, Peru, in 2025. Methods: A quantitative, quasi-experimental study was conducted in two localities: San Pablo de Cuyana (intervention group, 43 households) and Santa Rita del Nanay (control group, 60 households). The intervention included face-to face educational sessions using participatory strategies and illustrated materials aimed at strengthening malaria-related knowledge and promoting preventive practices. In both communities, a pre- and post-intervention survey was conducted to assess knowledge level, preventive practices, treatment adherence, and malaria incidence. Results: The educational intervention was implemented with active participation from 89% of the households in San Pablo de Cuyana. In this group, significant improvement...