Gastric secretion was studied with high histamine stimulation in a group of 31 patients with liver cirrhosis , comparing the results with the values ​​found in a group of normal people called controls and another group with duodenal ulcer. Patients with liver cirrhosis secrete very little hydrochloric acid, both in basal conditions and after a high histamine stimulation , being 1.77 ± 1.66 mEq DAB total HCl, and 7.13 ± 5.35 mEq DAM . This gastric hyposecretion not depend on the degree of hepatic decompensation. It is possible that a small number of parietal cells is due by chronic atrophic gastritis subsequent to the toxic effects of alcohol, malnutrition or some other factor . It would be interesting to study gastric secretion in alcoholics without cirrhosis and without cirrhosis in malnourished to explain this finding. In 24 cirrhotic patients undergoing upper gastrointestinal st...